A regulatory pathway, ecdysone-transcription factor relish-cathepsin L, is involved in insect fat body dissociation.

Insect fat body is the organ for intermediary metabolism, comparable to vertebrate liver and adipose tissue.Larval fat body is disintegrated to individual fat body cells and then adult fat body is remodeled at the pupal stage.However, little is known about the dissociation mechanism.We find that the moth Helicoverpa armigera cathepsin L (Har-CL) is

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Histone Deacetylase Inhibitors and Microtubule Inhibitors Induce Apoptosis in Feline Luminal Mammary Carcinoma Cells

Feline mammary carcinoma (FMC) is the third most common type of neoplasia in cats, sharing similar epidemiological features with human breast cancer.In humans, histone deacetylases (HDACs) play an important role in the regulation of gene expression, with HDAC inhibitors (HDACis) disrupting gene expression and leading to cell death.In parallel, micr

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